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When the liver is diseased, these parts begin to hurt

articleUseronApril 22, 2026

The liver is one of the most important organs in the body, as it performs fundamental functions such as blood detoxification, bile production, and nutrient storage.

However, when the liver does not function properly, it can manifest itself through various types of pain and discomfort in various parts of the body.

Main areas affected by liver problems

Below we explain the areas where you may experience pain or discomfort when you have liver problems.

1. Right upper abdomen

Pain in the upper right abdomen is one of the most common symptoms associated with liver problems. The liver is located just below the diaphragm, on the right side of the abdomen, so any inflammation, damage, or enlargement of the liver can cause pain in this region.

This pain can range from a feeling of heaviness or discomfort to a sharp or stabbing pain. Conditions such as fatty liver disease, hepatitis, or cirrhosis can cause this discomfort.

2. Back and right shoulder

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